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PRN Omega-3 for Dry Eye Shop De3 & Oe Liquid in Canada
PRN Omega 3 Canada:
Premium Fish Oil for Dry Eye & Eye Health
Looking for PRN Omega 3 in Canada?
mEYEspa carries authentic PRN De3 softgels and PRN Oe Liquid, with Canadian-dollar pricing and shipping from Ontario.
As an optometrist-led eye-care retailer, we can help you compare formulations, EPA and DHA concentrations, and package sizes to find the option best suited to your needs.
Softgels and Liquid - pure quality
from mEYEspa trusted by 15,000 Canadians
Not all Omega 3 supplements are created equal.
Consider PRN Omega-3 when choosing a supplement. It's not simply about how much fish oil is in the bottle! Consider the concentration of the good stuff (EPA and DHA,) the form of the fish oil, and choosing a quality, pure supplement that fits your needs.
Physician Recommended (PRN) supplements are formulated with concentrated marine omega-3 fatty acids in premium triglyceride form. Available in convenient softgels or easy-to-take liquid, PRN provides options for customers seeking quality nutritional supplementation.
At mEYEspa, we specialize in eye care and help Canadians make informed decisions about products that support their eye-health routines.
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Discover our PRN collection and choose the formulation that works best for you.
PRN De3 Dry Eye Benefits — 180 Softgels
High-Potency with Vitamin D3
PRN De3 delivers concentrated EPA and DHA in a premium re-esterified triglyceride fish oil formulation.
Each labelled three-softgel serving provides:
- 1,680 mg EPA
- 560 mg DHA
- 2,240 mg combined EPA + DHA
- Added vitamin D3
Why choose PRN De3?
An excellent choice for customers who prefer the convenience of a capsule-based omega-3 supplement with clearly identified EPA and DHA concentrations.
180 softgels per bottle (also available in 270 and 90).
PRN Oe Essentials — 200 mL Liquid
High-Potency without Swallowing Softgels
PRN Oe Liquid provides concentrated EPA and DHA in a premium triglyceride-form fish oil, offering an alternative to traditional softgels.
Each labelled 5 mL serving provides:
- 1,680 mg EPA
- 560 mg DHA
- 2,240 mg combined EPA + DHA
- Convenient liquid formulation
Why choose PRN Oe Liquid?
Ideal for customers who prefer liquid supplements, have difficulty swallowing capsules, or simply want the flexibility of a measured liquid serving.
200 mL bottle.
Why Choose PRN Instead of Ordinary Fish Oil?
1. It's What's Inside the Capsule That Matters
Many fish oil supplements prominently advertise 1,000 mg of fish oil per capsule. But that number does not tell you how much EPA and DHA you're actually receiving.
EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the key marine omega-3 fatty acids widely studied in nutrition, inflammation and ocular health.
PRN emphasizes concentrated EPA and DHA rather than simply total fish oil content.
The important comparison is not the size of the capsule. It's the amount of EPA and DHA it contains.
2. Premium Triglyceride-Form Omega-3
Not all fish oils are supplied in the same chemical form.
PRN uses triglyceride-form fish oil, including re-esterified triglycerides in its De3 formulation.
Some comparative studies have reported better omega-3 absorption from triglyceride-form oils than from ethyl-ester preparations under specific conditions.
Although absorption also depends on diet and individual factors, the formulation is worth considering when choosing an omega-3 supplement.
3. Developed With Eye Health in Mind
PRN has a particular focus on omega-3 supplementation within eye care.
Its re-esterified formulation has been investigated in published clinical research involving patients with dry eye disease and meibomian gland dysfunction.
Why Dr. Morris Recommends PRN Omega-3
"When patients ask me about Omega-3 supplements, I always encourage them to look beyond the glossy label.
Many supplements promote the total amount of fish oil without clearly emphasizing the actual EPA and DHA content. Those concentrations can vary considerably between products.
What I appreciate about PRN is the concentration of EPA and DHA, its triglyceride formulation and its focus on ocular health.
I have recommended PRN in clinical practice for years. It is a great option for patients interested in premium nutritional supplementation. As with all supplements, individual needs vary, and omega-3 should not be considered a replacement for appropriate dry eye diagnosis or treatment.
For patients considering a quality supplement, PRN is certainly a brand I believe deserves strong consideration."
— Dr. Morris, Optometrist | mEYEspa
Omega-3 for Dry Eye: What Does the Latest Clinical Research Say?
Omega-3 Supplementation in TFOS DEWS III (2025)
The Tear Film & Ocular Surface Society (TFOS) published its updated international dry eye management recommendations in 2025.
The TFOS DEWS III Management and Therapy Report recognizes dietary supplementation as an important consideration in dry eye management and reviews the growing evidence concerning omega-3 fatty acids.
The report highlights clinical research showing that omega-3 supplementation may improve several measures of dry eye disease, including:
- Tear breakup time (TBUT)
- Tear osmolarity
- Schirmer tear production measurements
- Patient-reported dry eye symptoms
- Conjunctival goblet cell density
Importantly, DEWS III cites a meta-analysis of 19 randomized controlled trials reporting statistically significant improvements in dry eye signs and symptoms with omega-3 supplementation.
Although not every study has demonstrated a benefit, the international consensus report continues to recognize a potential role for omega-3 fatty acids as part of individualized dry eye management.
PRN Omega-3: A Formulation Studied in Dry Eye Patients
A 2016 randomized, double-masked clinical trial published in Cornea specifically investigated a PRN re-esterified triglyceride omega-3 formulation in patients with dry eye disease and meibomian gland dysfunction.
Participants receiving omega-3 supplementation demonstrated statistically significant improvements compared with controls in tear osmolarity, tear breakup time and patient-reported dry eye symptoms over 12 weeks.
The study provides encouraging evidence concerning the particular formulation and clinical population investigated.
Why the Type of Omega-3 Matters
Fish oil supplements vary considerably in their concentrations of EPA and DHA, chemical form and recommended serving sizes.
PRN De3 and PRN Oe Liquid provide concentrated EPA and DHA in triglyceride-form formulations.
For individuals considering omega-3 supplementation as part of their eye-care routine, understanding these differences is an important part of making an informed choice.
Dr. Morris's perspective: Both supplementation and increased intake are options worth considering as part of a comprehensive dry eye management plan. Supplementation is often required to achieve the levels required for effect but should be used alongside, rather than replacing, appropriate diagnosis, lubricating drops, lid hygiene and other treatments when indicated.
References
- Jones L, et al. TFOS DEWS III: Management and Therapy. American Journal of Ophthalmology. 2025;279:289–386. https://doi.org/10.1016/j.ajo.2025.05.039
- Epitropoulos AT, et al. Effect of Oral Re-esterified Omega-3 Nutritional Supplementation on Dry Eyes. Cornea. 2016;35(9):1185–1191. https://pmc.ncbi.nlm.nih.gov/articles/PMC4975557/
- Dry Eye Assessment and Management Study Research Group. n−3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease. New England Journal of Medicine. 2018;378:1681–1690. https://doi.org/10.1056/NEJMoa1709691
PRN De3 vs. PRN Oe Liquid: Which One Should You Choose?
Both PRN formulations provide concentrated EPA and DHA. The main differences are how they are taken and their additional ingredients.
Choose PRN De3 Softgels If You:
- Prefer the convenience of capsules.
- Want an omega-3 formula that also contains vitamin D3.
- Prefer a pre-portioned supplement.
- Are comfortable swallowing softgels.
- 90 softgels — Smaller initial purchase
- 180 softgels — Best price per softgel
- 270 softgels — Convenient larger supply with free shipping
Choose PRN Oe Liquid If You:
- Prefer not to swallow capsules.
- Want a liquid omega-3 supplement.
- Prefer measuring your serving.
- Want an alternative to gelatin softgels.
Both provide 2,240 mg combined EPA and DHA per labelled serving.
The best choice is the product that matches your nutritional needs, personal preferences and the advice of your healthcare professional.
Canadian · Optometrist Approved Eye Care · CAD$ Pricing
Fast shipping from Ontario · Mix & Match Savings · Live Expiry Dates
Up to $10 Cashback Rewards on PRN
Learn More About why PRN is a good choice from an Optometrist...
Watch this Optometrist video for additional discussion about PRN.
For product-specific directions and ingredients, always refer to the current Canadian product labels.
What Our Customers Say About PRN
At mEYEspa, we know that purchasing a premium nutritional supplement is an important decision.
Read feedback from customers who have purchased PRN Omega-3 through our Canadian eye-care store.
Link to all reviews at judge.me > See Product Reviews
Frequently Asked Questions About PRN Omega-3
What makes PRN Omega-3 different from regular fish oil?
PRN emphasizes concentrated EPA and DHA in premium triglyceride-form fish oil. When comparing omega-3 products, it's important to examine the actual EPA and DHA amounts per serving rather than relying solely on total fish oil content.
Can PRN Omega-3 help with dry eyes?
Some clinical studies involving omega-3 supplementation have reported improvements in dry eye signs and symptoms. However, other high-quality studies have not found significant benefits compared with placebo. Results vary, and omega-3 supplementation should not replace appropriate dry eye treatment.
How much EPA and DHA does PRN De3 contain?
The current De3 product provides 1,680 mg EPA and 560 mg DHA per labelled three-softgel serving, for a total of 2,240 mg EPA and DHA.
Is PRN liquid as concentrated as PRN De3?
Yes. The two products provide the same stated EPA and DHA amounts per labelled serving: three De3 softgels or 5 mL of PRN Oe Liquid.
How long does a bottle last?
A 180-softgel De3 bottle provides 60 three-softgel servings. A 200 mL liquid bottle provides 40 servings of 5 mL each.
The actual duration depends on the daily dosage recommended for you. Follow the current product label or your healthcare professional's instructions.
Is PRN Omega-3 better absorbed than other fish oils?
Triglyceride and re-esterified triglyceride fish oils have demonstrated absorption advantages over some ethyl-ester formulations in certain studies. However, bioavailability also depends on meal composition, dose and individual physiology. Higher absorption does not necessarily establish better clinical outcomes for dry eye.
Can I take PRN Omega-3 with my dry eye drops?
Nutritional supplements and eye drops serve different purposes. They may both form part of an individualized eye-care regimen. Consult your optometrist about which treatments are appropriate for your particular condition.
Where can I buy PRN Omega-3 in Canada?
PRN De3 and PRN Oe Liquid are available through mEYEspa, a Canadian, optometrist-led eye-care retailer. Prices are displayed in Canadian dollars, with shipping options shown at checkout.
Worried about fake supplements from marketplaces?
Shop confidently with clear expiration dates and guaranteed authenticity. Worried about fake vitamins and eye drops on marketplaces? mEYEspa has you covered.
Ready to Choose Your Omega-3?
Concentrated EPA and DHA. Premium fish oil formulations. Trusted Canadian eye-care guidance.
Whether you prefer convenient De3 softgels or easy-to-take Oe Liquid, mEYEspa makes it simple to purchase PRN Omega-3 online in Canada.
Choose your preferred product and enjoy secure checkout, Canadian-dollar pricing and shipping options designed for Canadian customers.
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Free shipping available on qualifying orders over $149.
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Product information: Supplement quantities are presented according to the current stated product servings. Follow the authorized Canadian product label for directions and precautions. Consult a healthcare professional before use if you take medication, have a medical condition, are pregnant or breastfeeding, or are scheduled for surgery. Fish-derived products are not appropriate for individuals with relevant allergies unless cleared by their healthcare professional.
Disclaimer: Nutritional supplements are not intended to replace professional diagnosis or prescribed dry eye treatment. Clinical studies do not establish that every patient will experience symptom improvement.
https://www.meyespa.com/pages/author-dr-jason-morris
Away from corporate influences and their churn, I believe in time and an unhurried environment. At mEYEspa and my clinic, we are UNcorporate Optometry. I have special interest in occupational vision needs, concussive injury to the visual system and dry eye management. I am the owner of mEYEspa and a dedicated to the delivery of relevant information and clinic-tested eye care products. -Doctor of Optometry - University of Waterloo 1994 -Honors Bachelor of Science – Waterloo 1994 -Registered Ontario College of Optometrists -Member of Ontario Association of Optometrists -Member of Canadian Association of Optometrists -10 year straight winner of 3 Best Rated Optometrists London ON
