Buy Thealoz TOTAL Eye Drops for Dry, Red, Irritated Eyes
Preservative-free dry eye relief with added NAAGA. Suitable for use with contact lenses.
When irritated dry eyes also look chronicically red, choosing the right clinic grade eye drop can help!. Thealoz TOTAL eye drops combine the hydrating and protective ingredients found in Thealoz DUO plus add NAAGA, an additional ingredient that helps reduce redness of the ocular surface.
At mEYEspa, we recommend considering Thealoz TOTAL when dry-eye-related redness is the chief concern. It supports comfort during prolonged screen use and exposure to dry environments.
✓ Best For
- Dry eyes with chronic redness and irritation.
- Contact lens wearers seeking preservative-free lubrication.
- People interested in the familiar Thealoz ingredient combination with added redness support.
- Computer users whose dry eye symptoms also include redness and screen discomfort/blur.
Dr. Morris’ Comments
“Thealoz DUO is one of our top-selling drops and remains a favourite recommendation for computer and screen-related dryness. I liked my own trial of Thealoz TOTAL eye drops and began recommended in clinic immediately. Its added NAAGA ingredient makes it a welcome option with chronic dry-eye-related redness with the irritation. Contact lens compatibility is another great advantage.”
— Dr. Jason Morris, Optometrist
Three Complementary Ingredients
Trehalose 3% — protection and hydration
Trehalose helps protect the delicate ocular surface against drying stress. It supports hydration and complements the lubricating action of hyaluronic acid. This is one of the familiar ingredients that makes Thealoz DUO a popular part of many dry eye routines.
Hyaluronic acid 0.15% — lubrication and moisture retention
Present as sodium hyaluronate, hyaluronic acid attracts and retains water. It helps lubricate the eye’s surface, supporting smoother, more comfortable blinking when eyes feel dry. See more info here
NAAGA 2.45% — added redness support
N-acetylaspartylglutamic acid, or NAAGA, is the additional ingredient that distinguishes Thealoz TOTAL eye drops from Thealoz DUO. The manufacturer describes this naturally occurring peptide as helping calm early-onset inflammation. Its inclusion makes TOTAL a highly effetive option worth considering when dryness is accompanied by redness and irritation. Redness has show to improve progressively with use. NAAGA is not an eye whitener like Lumify.
Relief for Dry-Eye-Related Redness
An irritated, dry ocular surface can leave your eyes looking red as well as feeling uncomfortable. Thealoz TOTAL eye drops combines lubrication, hydration and soothing support to help address this combination of symptoms.
The formula contains no blood-vessel-constricting redness remover. Its focus is on supporting the ocular surface and relieving dry eye discomfort.
Clinical evidence (see reference below): A 2024 study involving 62 people with moderate-to-severe dry eye found that conjunctival redness improved in 96.8% of participants after 42 days using the hyaluronic acid–trehalose–NAAGA formulation. This was an uncontrolled study of the complete formula; it did not isolate NAAGA’s effect or compare TOTAL directly with DUO.
Contact Lens Compatible
Thealoz TOTAL is suitable for use with contact lenses, making it a convenient choice for lens wearers who experience dry eye discomfort.
The preservative-free formula provides lubrication without exposing your eyes to preservatives in the drops. This can be particularly useful when contact lens wear overlaps with long screen sessions, air conditioning or indoor heating.
Comfort drops should complement good contact lens habits, including appropriate wearing time and replacement schedules. If your eyes become red or painful while wearing lenses, remove them and seek advice from your eye care professional.
Thealoz TOTAL vs. Thealoz DUO
Both formulas provide preservative-free hydration and ocular surface protection. At mEYEspa, we emphasize different everyday needs when helping you choose:
| Feature | Thealoz TOTAL | Thealoz DUO |
|---|---|---|
| Our main focus | Dry-eye-related redness, irritation and contact lens comfort | Computer and screen-related dry eye |
| Trehalose 3% | Yes | Yes |
| Hyaluronic acid 0.15% | Yes | Yes |
| Added NAAGA 2.45% for redness/inflammation | Yes | No |
| Preservative-free | Yes | Yes |
| Contact lens compatible | Yes | Yes |
| Suitable for screen-related dryness | Yes | Yes |
Already comfortable with Thealoz DUO? There is no automatic need to switch. TOTAL offers another option when redness and irritation influence your choice of drop.
Preservative-Free Convenience
Thealoz TOTAL uses Théa’s patented ABAK delivery system in an easy-to-squeeze bottle.
- Preservative-free and phosphate-free.
- Approximately 300 drops per bottle.
- Calibrated drop delivery.
- Suitable for use for up to three months after opening.
Write the opening date on the bottle or carton. Replace it three months after opening, even if some solution remains, and always observe the printed expiry date.
How to Use Thealoz TOTAL
Gently pull down your lower eyelid and apply the drop into the pocket between the lid and eye. Avoid touching the bottle tip to your eye, fingers or other surfaces. Replace the cap after use.
Follow the package instructions for dosing, storage and spacing between different eye products, or the advice of your eye care professional. Do not share your bottle.
Is Thealoz TOTAL Right for You?
If dry-eye-related redness, irritation or contact lens dryness are your main concerns, Thealoz TOTAL is worth considering. It combines familiar hydration and protection with added NAAGA. Consider TOTAL if you have dry eye secondary to another condition like: Thyroid Eye Disease, Lupus, Diabetes or Sjögren's disease..
No single drop suits every dry eye problem. Persistent redness deserves assessment, and eye pain, light sensitivity, discharge or changes in vision require prompt eye care professional attention.
Clinical Evidence
Studies supporting the use of Sodium Hyaluronate / Hyaluronic Acid for the treatment of Dry eye:
- NIH National Library of Medicine 2022 > Hyaluronic acid in the treatment of dry eye disease
- MDPI 2022 > Evaluation of Dry Eye Treatment with Sodium Hyaluronate- and Dexpanthenol-Containing Eye Drops
- ResearchGate 2006 > Effectiveness of sodium hyaluronate eyedrops in the treatment of dry eye
- Clinical Ophthalmology 2018 > Trehalose/hyaluronate eyedrop effects on ocular surface inflammatory markers and mucin expression in dry eye patients
- El Fekih L, et al. (2024). Successful management of dry eye disease with a new eye drop formulation combining hyaluronic acid, trehalose, and N-acetyl-aspartyl-glutamic acid (NAAGA). Journal Français d’Ophtalmologie, 47(7), 104169. Read the study.
Related Topics: How can non-preserved eyedrops like Thealoz DUO last longer that preserved?, Acute vs. Chronic Dry Eye, Dry Eye Basics

